Found 9 matching trials
A Study of the Safety, Tolerability, and Absorption, Metabolism, and Excretion of PA-824 in Healthy Adult Male Subjects. PHASE1 This study is a Phase 1, single-center, open-label, single-dose study to ev...
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Covance Clinical Research Unit
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Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z) PHASE2 The trial will evaluate the extended bactericidal activity of 14 consecutiv...
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Centre for Tuberculosis Research Innovation, UCT Lung Institute
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Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis PHASE3 To evaluate the efficacy, safety and tolerability of various doses and dura...
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National Center for Tuberculosis and Lung Diseases
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Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary Tuberculosis PHASE2 The goal of this clinical trial is to evaluate 3 dose levels of TBAJ876 for...
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Active Not Recruiting
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National Center for Tuberculosis and Lung Diseases
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Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002) PHASE2 The purpose of this study is to assess the mycobactericidal activity of the...
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Task Applied Science, Karl Bremer Hospital
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Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001) PHASE2 The trial will evaluate the extended bactericidal activity of 14 consecutiv...
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Centre for Tuberculosis Research Innovation, UCT Lung Institute
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A Phase 3 Trial Assessing Safety and Efficacy of B-Pa-L in Participants With DR-TB PHASE3 The purpose of this study is to evaluate the efficacy, safety, tolerability...
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Task Applied Science - Brooklyn Chest Hospital
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A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis PHASE2 Pretomanid is being used in an antimicrobial combination regimen(s) to trea...
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National Center for Tuberculosis and Lung Diseases
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Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients PHASE2 To evaluate the efficacy, safety and tolerability at 8 weeks (2-months), 52...
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